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`NYSCEF DOC. NO. 141
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`INDEX NO. 190307/2013
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`RECEIVED NYSCEF: 05/10/2019
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`
`
`
`
`Exhibit C –
`Reliance Materials Part 1
`
`
`
`FILED: NEW YORK COUNTY CLERK 05/10/2019 04:01 PM
`NYSCEF DOC. NO. 141
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`INDEX NO. 190307/2013
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`RECEIVED NYSCEF: 05/10/2019
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`8MI
`IM
`ife
`
`American
`Cancer
`Society
`
`r
`i
`Cancer Facts & Figures
`2018
`
`*m
`
`MS
`36,170
`
`[gn
`
`E
`
`m
`
`B
`
`S03
`
`» CA
`k 178,130
`
`MT
`6C 0
`
`WY
`2,780
`
`2';,570
`
`|i5j«
`9,730
`
`m
`
`HI6,280 ^
`
`MN
`■- 31,270 -
`
`a®4oo
`
`100301
`
`18,130
`
`2/,830
`
`mmm
`
`^1 b,y20
`'CT 21,240
`MJ 53,260
`DE 6,110
`MD 33,810
`DC 3,260
`
`‘>■3,130
`
`30,450
`
`mm
`lilii
`m135,170
`
`PR
`N/A
`
`Estimated numbers of new cancer cases for 2018, excluding basal cell and squamous cell skin cancers and in situ carcinomas except urinary bladder.
`Estimates are not available for Puerto Rico.
`Note: State estimates are offered as a rough guide and should be interpreted with caution. State estimates may not add to US total due to rounding
`
`Special Section: Ovarian Cancer
`see page 28
`
`
`
`FILED: NEW YORK COUNTY CLERK 05/10/2019 04:01 PM
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`INDEX NO. 190307/2013
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`RECEIVED NYSCEF: 05/10/2019
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`Contents
`Basic Cancer Facts
`Figure 1. Trends in Age-adjusted Cancer Death Rates by Site,
`Males, US, 1930-2015
`Figure 2. Trends in Age-adjusted Cancer Death Rates by Site,
`Females, US, 1930-2015
`Table 1. Estimated Number of New Cancer Cases and Deaths
`by Sex, US, 2018
`Table 2. Estimated Number of New Cases for Selected
`Cancers by State, US, 2018
`Table 3. Estimated Number of Deaths for Selected Cancers
`by State, US, 2018
`Table 4. Incidence Rates for Selected Cancers by State,
`US, 2010-2014
`Table 5. Death Rates for Selected Cancers by State,
`US, 2011-2015
`
`Selected Cancers
`Figure 3. Leading Sites of New Cancer Cases and Deaths
`2018 Estimates
`Table 6. Probability (%) of Developing Invasive Cancer
`during Selected Age Intervals by Sex, US, 2012-2014
`Table 7. Trends in 5-year Relative Survival Rates (%)
`by Race, US, 1975-2013
`..........
`Table 8. Five-year Relative Survival Rates (%) by Stage
`at Diagnosis, US, 2007-2013
`
`Special Section: Ovarian Cancer
`Figure SI. Female Reproductive Anatomy
`Figure S2. Distribution (%) of Major Types of Ovarian
`Cancer by Race/Ethnicity, 2010-2014
`Table SI. Age-specific Probability of Developing Ovarian
`Cancer for US Women
`
`1
`
`2
`
`3
`
`4
`
`5
`
`6
`
`7
`
`9
`
`10
`
`14
`
`18
`
`21
`
`28
`28
`
`29
`
`30
`
`Figure S3. Ovarian Cancer Incidence and Mortality Rates
`by Race and Ethnicity, US, 2010-2014
`Figure S4. Epithelial Ovarian Cancer Incidence Rates by
`Age and Race, US, 2010-2014
`Figure S5. Age-adjusted Ovarian Cancer Mortality Rates
`by Age Group and Race/Ethnicity, 1975-2015
`Table S2. Relative Risks for Established Ovarian Cancer
`Risk Factors
`Figure S6. Stage Distribution (%) for Ovarian Cancer
`by Flistology, US, 2007-2013
`Table S3. Five-year Cause-specific Survival Rates (%)
`for Ovarian Cancer by Stage at Diagnosis and Race/Ethnicity,
`US, 2007-2013
`Table S4. Five-year Relative Survival Rates (%) for Ovarian
`Cancer by Stage at Diagnosis and Histology, US, 2007-2013
`
`Tobacco Use
`Figure 4. Proportion of Cancer Deaths Attributable to
`Cigarette Smoking in Adults 30 Years and Older, US, 2014
`
`Nutrition & Physical Activity
`
`Cancer Disparities
`Table 9. Incidence and Mortality Rates for Selected Cancers
`by Race and Ethnicity, US, 2010-2015
`
`The Global Cancer Burden
`
`The American Cancer Society
`
`Sources of Statistics
`American Cancer Society Recommendations for the Early
`Detection of Cancer in Average-risk Asymptomatic People
`
`30
`
`31
`
`32
`
`34
`
`36
`
`37
`
`37
`
`44
`
`45
`
`48
`
`52
`
`54
`
`55
`
`57
`
`68
`
`71
`
`This publication attempts to summarize current scientific information about cancer.
`Except when specified, it does not represent the official policy of the American Cancer Society.
`
`Suggested citation: American Cancer Society. Cancer Facts & Figures 2018.
`Atlanta: American Cancer Society; 2018.
`
`Global Headquarters: American Cancer Society Inc.
`250 Williams Street, NW, Atlanta, GA 30303-1002
`404-320-3333
`©2018, American Cancer Society, Inc. All rights reserved,
`including the right to reproduce this publication
`or portions thereof in any form.
`For written permission, address the Legal department of
`the American Cancer Society, 250 Williams Street, NW,
`Atlanta, GA 30303-1002.
`
`
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`What Is Cancer?
`Cancer is a group of diseases characterized by the
`uncontrolled growth and spread of abnormal cells. If the
`spi'ead is not controlled, it can result in death. Although
`the reason why the disease develops remains unknown
`for many cancers, particularly those that occur during
`childhood, there are many known cancer causes,
`including lifestyle factors, such as tobacco use and excess
`body weight, and non-modifiable factors, such as
`inherited genetic mutations, hormones, and immune
`conditions. These risk factors may act simultaneously or
`in sequence to initiate and/or promote cancer growth.
`
`Can Cancer Be Prevented?
`A substantial proportion of cancers could be prevented,
`including all cancers caused by tobacco use and other
`unhealthy behaviors. According to a recent study by
`American Cancer Society epidemiologists, at least 42% of
`newly diagnosed cancers in tbe US - about 729,000 cases
`in 2018 - are potentially avoidable, including 19% that are
`caused by smoking and 18% that are caused by a
`combination of excess body weight, physical inactivity,
`excess alcohol consumption, and poor nutrition. Certain
`cancers caused by infectious agents, such as human
`papillomavirus (HPV), hepatitis B virus (HBV), hepatitis
`C virus (UCV), and Helicobacter pylori (H. pylori), could be
`prevented through behavioral changes, vaccination, or
`treatment of the infection. Many of the more than 5
`million skin cancer cases that are diagnosed annually
`could be prevented by protecting skin from excessive sun
`exposure and not using indoor tanning devices.
`
`Screening can help prevent colorectal and cervical cancers
`by allowing for the detection and removal of precancerous
`lesions. Screening also offers the opportunity to detect
`some cancers early, when treatment is more likely to be
`successful. Screening is known to help reduce mortality
`for cancers of the breast, colon, rectum, cervix, and lung
`(among long-term current or former heavy smokers). In
`addition, a heightened awareness of changes in certain
`parts of the body, such as the breast, skin, mouth, eyes, or
`
`genitalia, may also result in the early detection of cancer.
`For complete cancer screening guidelines, see page 71.
`
`How Many People Alive Today Have
`Ever Had Cancer?
`More than 15.5 million Americans with a history of
`cancer were alive on January 1, 2016. Some of these
`individuals were diagnosed recently and are still
`undergoing treatment, while most were diagnosed many
`years ago and have no current evidence of cancer.
`
`How Many New Cases and Deaths Are
`Expected to Occur in 2018?
`About 1.7 million new cancer cases ai'e expected to be
`diagnosed in 2018 (Table 1, page 4). This estimate does not
`include carcinoma in situ (noninvasive cancer) of any site
`except urinary bladder, nor does it include basal cell or
`squamous cell skin cancers because these are not required
`to be reported to cancer registries. Table 2 (page 5)
`provides estimated new cancer cases in 2018 by state.
`
`About 609,640 Americans are expected to die of cancer
`in 2018 (Table 1, page 4), which translates to about 1,670
`deaths per day. Cancer is the second most common cause
`of death in the US, exceeded only by heart disease. Table 3
`(page 6) provides estimated cancer deaths by state in 2018.
`
`How Much Progress Has Been Made
`against Cancer?
`Cancer death rates are the best measure of progress
`against cancer because they are less affected by detection
`practices than incidence and survival. The overall age-
`adjusted cancer death rate rose during most of the 20th
`century mainly because of the tobacco epidemic, peaking
`in 1991 at 215 cancer deaths per 100,000 people. As of
`2015, the rate had dropped to 159 per 100,000 (a decline of
`26%) because of reductions in smoking, as well as
`improvements in early detection and treatment. This
`decline translates into more than 2.3 million fewer
`cancer deaths from 1991 to 2015, progress that has been
`driven by rapid declines in death rates for the four most
`common cancer types - lung, colorectal, breast, and
`prostate (Figure 1, page 2 and Figure 2, page 3).
`
`Cancer Facts & Figures 2018
`
`1
`
`
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`Do Cancer Incidence and Death Rates
`Vary by State?
`Tables 4 (page 7) and 5 (page 8) provide average annual
`incidence (new diagnoses) and death rates for selected
`cancer types by state. The variation by state is largest for
`lung cancer, reflecting historical and recent differences
`in smoking prevalence.
`
`Who Is at Risk of Developing Cancer?
`Cancer usually develops in older people; 87% of all
`cancers in the United States are diagnosed in people 50
`years of age or older. Certain behaviors also increase risk,
`such as smoking, eating an unhealthy diet, or not being
`physically active. In the US, approximately 40 out of 100
`men and 38 out of 100 women will develop cancer during
`their lifetime (Table 6, page 14). These probabilities are
`estimated based on cancer occurrence in the general
`population and may overestimate or underestimate
`individual risk because of differences in exposures (e.g.,
`smoking), family history, and/or genetic susceptibility.
`
`Relative risk is the strength of the relationship between
`exposure to a given risk factor and cancer. It is measured
`by comparing cancer occurrence in people with a certain
`exposure or trait to cancer occurrence in people without
`this characteristic. For example, men and women who
`smoke are about 25 times more likely to develop lung
`cancer than nonsmokers, so their relative risk of lung
`cancer is 25. Most relative risks are not this large. For
`example, women who have a mother, sister, or daughter
`with a history of breast cancer are about twice as likely to
`develop breast cancer as women who do not have this
`family history; in other words, their relative risk is about
`2. For most types of cancer, risk is higher with a family
`history of the disease, which is thought to result from the
`inheritance of genetic variations that confer low or
`moderate risk and/or similar exposures to lifestyle/
`environmental risk factors among family members. Only
`a small proportion of cancers are strongly hereditary,
`meaning they are caused by an inherited genetic
`alteration that confers a very high risk.
`
`Figure 1. Trends in Age-adjusted Cancer Death Rates* by Site, Males, US, 1930-2015
`
`100
`
`80
`
`Lung & bronchus
`
`.. Stomach
`
`,, Colon & rectum
`
`Prostate
`
`X
`
`co 3Q
`
`.
`
`OQ. 60
`
`01
`03
`
`Eo
`
`o
`o
`o 40
`01
`D.
`01
`tt3
`Cd
`
`20
`
`... Liver'!’
`
`Pancreas'!’
`
`MSSSUttrsS-S'JiSii
`
`.1 I i I i I i
`I I I I
`I I I I
`I. .1 . I I I i
`I .i I i
`-lI
`1960
`1965
`1955
`1940
`1945
`1950
`1935
`1930
`1980
`1985
`1975
`I *Age adjusted to the 2000 US standard population. tMortality rates for pancreatic and liver cancers are increasing.
`I Note: Due to changes in ICD coding, numerator information has changed over time. Rates for cancers of the liver, lung and bronchus, colon and rectum, and uterus are
`j affected by these coding changes.
`I Source: US Mortality Volumes 1930 to 1959, US Mortality Data 1960 to 2015, National Center for Health Statistics, Centers for Disease Control and Prevention,
`I
`©2018, American Cancer Society, Inc., Surveillance Research
`
`1 I 1
`I I 1
`1970
`
`1990
`
`0
`
`2
`
`Cancer Facts & Figures 2018
`
`1111
`
`1995
`
`I I I
`2000
`
`±L
`2005
`
`J_J_L.1_.L_1.J_
`2015
`2010
`
`
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`What Percentage of People
`Survive Cancer?
`Over the past three decades, the 5-year relative survival
`rate for all cancers combined increased 20 percentage
`points among whites and 24 percentage points among
`blacks, yet it remains substantially lower for blacks (70%
`versus 63%, respectively). Improvements in survival
`(Table 7, page 18) reflect improvements in treatment, as
`well as earlier diagnosis for some cancers. Survival varies
`greatly by cancer type and stage at diagnosis (Table 8,
`page 21).
`
`Relative survival, the survival statistic used throughout
`this report, is the proportion of people with cancer who
`are alive for a designated time (usually 5 years) after
`diagnosis divided by the proportion of people of similar
`age, race, etc. expected to be alive in the absence of
`cancer based on normal life expectancy. Relative survival
`does not distinguish between patients who have no
`evidence of cancer and those who have relapsed or are
`
`still in treatment, nor does it represent the proportion of
`people who are cured because cancer death can occur
`beyond 5 years after diagnosis. For information about
`how survival rates were calculated for this report, see
`Sources of Statistics on page 68.
`
`Although relative survival rates provide some indication
`about the average experience of cancer patients in a given
`population, they should be interpreted with caution for
`several reasons. First, 5-year survival rates do not reflect
`the most recent advances in detection and treatment
`because they are based on patients who were diagnosed
`several years in the past. Second, they do not account for
`many factors that affect individual survival, such as
`treatment, other illnesses, and biological or behavioral
`differences. Third, improvements in survival rates over
`time do not always indicate progress against cancer. For
`example, increases in average survival rates occur when
`screening results in the detection of cancers that would
`never have caused harm if left undetected (overdiagnosis)
`and early diagnosis that does not increase lifespan.
`
`Figure 2. Trends in Age-adjusted Cancer Death Rates* by Site, Females, US, 1930-2015
`
`100
`
`80
`
`60
`
`40
`
`20
`
`.
`
`.
`
`.
`
`Stomach
`
`Liver'*'
`
`Uterus^
`
`Lung & bronchus
`
`Colon & rectum ' '
`
`Breast
`
`Pancreas
`
`co 0
`
`3 Q
`
`OQ
`
`01
`
`03Ea;
`o
`
`oo
`
`oo O
`
`)Q
`
`<v
`03
`
`0
`
`I I . i
`1930
`
`±L
`Jill
`1935
`1940
`
`1945
`
`1950
`
`i I I I
`1955
`1960
`
`1
`1965
`
`1970
`
`1975
`
`I I I I
`1 I I I
`1980
`1985
`1990
`
`1995
`
`.1...I...J....L
`
`2000
`
`2005
`
`2010
`
`2015
`
`*Age adjusted to the 2000 US standard population. tUterus refers to uterine cervix and uterine corpus combined. tThe mortality rate for liver cancer is increasing.
`Note: Due to changes in ICD coding, numerator information has changed over time. Rates for cancers of the liver, lung and bronchus, colon and rectum, and uterus are
`affected by these coding changes.
`Source: US Mortality Volumes 1930 to 1959, US Mortality Data 1960 to 2015, National Center for Health Statistics, Centers for Disease Control and Prevention,
`©2018, American Cancer Society, Inc., Surveillance Research
`
`Cancer Facts & igures 2018
`
`3
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`NYSCEF DOC. NO. 141
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`Table 1. Estimated Number* of New Cancer Cases and Deaths by Sex, US, 2018
`Estimated New Cases
`Male
`'85S37Q
`...37T60
`12.490
`7,980
`14,250
`2,440
`"181,960
`13,480
`16,520
`5,430
`49,690
`25,920
`2,960
`30,610
`5,450
`29,200
`2,700
`136,400
`10.490
`121,680
`4,230
`1,940
`,
`.... 7"370
`
`55,150
`5,200
`" "2,550
`"i'76,320'
`
`Female
`878,980
`14,380
`4,620
`5,600
`3,340
`820
`137,200
`3,810
`9,720
`5,040
`47,530
`17,110
`5,620
`11,610
`6,740
`26.240
`3,780
`'l"l"6',890
`2,660
`112,350
`1,880
`1,510
`..5"676
`'"39,200"
`36,120
`3,080
`'26"6"T26
`'110,070"
`13.240
`63,230
`22.240
`6,190
`5,170
`
`I
`
`!
`;
`
`:
`
`Both sexes
`609,640
`..T6"036'
`2,510
`2,650
`3,230
`1,640
`"T66"820
`15,850
`10,800
`1,450
`50,630
`
`Estimated Deaths
`Male
`323,630
`...7,280
`1,750
`1,770
`2,480
`1,280
`'"'94,230
`12,850
`6,510
`810
`27,390
`
`480
`20,540
`1,530
`23,020
`1,100
`87,200
`2,970
`83,550
`680
`930
`2,770
`"9,070
`5,990
`3,080
`480
`30,210
`
`Female
`286,010
`""2,"750
`760
`880
`750
`360
`66,590
`3,000
`4,290
`640
`23,240
`
`680
`9,660
`2,260
`21,310
`1,510
`7l','570
`740
`70,500
`330
`660
`2,380
`..4,39b'
`3.330
`1,060
`4"o","9'2"0
`32T20
`4,170
`11,350
`14,070
`1,200
`1.330
`
`i Both sexes
`; All sites
`1,735,350
`Oral cavity & pharynx
`51,540"
`17.110
`Tongue
`13,580
`Mouth
`17,590
`Pharynx
`Other oral cavity
`3,260
`Digestive system
`319,160
`Esophagus
`17,290
`Stomach
`26,240
`Small intestine
`10,470
`97.220
`Colon!
`43,030
`Rectum
`Anus, anal canal, & anorectum
`1,160
`8,580
`42.220
`Liver & intrahepatic bile duct
`30,200
`12,190
`Gallbladder & other biliary
`3,790
`44.330
`55,440
`Pancreas
`Other digestive organs
`2,610
`6,480
`Respiratory system
`"'l'5'8,770
`...253,296"
`3,710
`13,150
`Larynx
`Lung & bronchus
`154,050
`234,030
`Other respiratory organs
`1,010
`6.110
`I Bones & joints
`....1,590
`3,450
`13,040
`Soft tissue (including heart)
`....5J50
`' 99,550
`Skin (excluding basal & squamous)
`..l'3,46b"
`91,270
`Melanoma of the skin
`9,320
`8,280
`Other nonepithelial skin
`4,140
`268'67b
`i Breast
`44^400
`62.330
`i Genital system
`286,390
`13.240
`1
`Uterine cervix
`4,170
`i
`Uterine corpus
`11,350
`63,230
`22.240
`I
`14,070
`Ovary
`6,190
`1,200
`Vulva
`vagin* & other genital, female
`1,330
`5,170
`Prostate
`29,430
`29,430
`164,690
`164,690
`400
`400
`9,310
`9,310
`Testis
`Penis & other genital, rnale
`380
`380
`2,320
`2,320
`Urinary system
`10,060
`33,170
`23,110
`107,600
`42,750
`150,350
`62.380
`Urinary bladder
`4,720
`17,240
`12,520
`18,810
`81,190
`Kidney & renal pelvis
`4,960
`14,970
`10,010
`22,660
`65,340
`42,680
`Ureter & other urinary organs
`380
`580
`960
`1,280
`2,540
`3,820
`; Eye & orbit
`..2,130
`190
`160
`1,410
`350
`3,540
`16,830
`' 13,720'
`i Brain & other nervous system
`'23,880
`7,340
`9.490
`10,160
`"'14,350'
`3,080
`Endocrine system
`42',b'8'o"
`"1,590"
`1.490
`56,430
`2,060
`13,090
`1,100
`960
`40,900
`53,990
`Thyroid
`1,020
`1,260
`Other endocrine
`490
`530
`1,180
`2,440
`20','9"6'0
`"46,570
`Lymphoma
`83',180'
`8,830
`12,130
`36,610
`1,050
`4,840
`Hodgkin lymphoma
`430
`620
`3,660
`8,500
`11,510
`19,910
`41,730
`Non-Hodgkin lymphoma
`8,400
`32,950
`74,680
`12,7 70
`' 6,830"
`16,400
`Myeloma
`30,'7'7'b"
`5,940
`14,370
`24,370
`' 35,030
`14,270"
`25^270
`6b,300
`10,100
`Leukemia
`1,470
`3,290
`Acute lymphocytic leukemia
`640
`830
`2,670
`5,960
`4,510
`Chronic lymphocytic leukemia
`1,720
`2,790
`12,990
`7,950
`20,940
`10,670
`10.380
`Acute myeloid leukemia
`6,180
`4,490
`9,140
`19,520
`1,090
`4,980
`Chronic myeloid leukemia
`470
`3,450
`620
`8,430
`6,630
`Other leukemiat
`2,780
`3,850
`3,390
`2,060
`5,450
`Other & unspecified primary sites!
`20','610
`23,9'5b"
`l"5',"2'90
`4'4'''560
`31,810"
`16,520
`‘Rounded to the nearest 10; cases exclude basal cell and squamous cell skin cancer and in situ carcinoma except urinary bladder. About 63,960 cases of carcinoma in
`; situ of the female breast and 87,290 cases of melanoma in situ will be diagnosed in 2018. tDeaths for colon and rectal cancers are combined because a large number of
`j deaths from rectal cancer are misclassified as colon. TMore deaths than cases may reflect lack of specificity in recording underlying cause of death on death certificates
`i and/or an undercount in the case estimate.
`i Source: Estimated new cases are based on 2000-2014 incidence data reported by the North American Association of Central Cancer Registries (NAACCR). Estimated
`i deaths are based on 2001-2015 US mortality data. National Center for Health Statistics, Centers for Disease Control and Prevention,
`©2018, American Cancer Society, Inc., Surveillance Research
`
`4
`
`Cancer Facts & Figures 2018
`
`
`
`FILED: NEW YORK COUNTY CLERK 05/10/2019 04:01 PM
`NYSCEF DOC. NO. 141
`
`INDEX NO. 190307/2013
`
`RECEIVED NYSCEF: 05/10/2019
`
`Table 2. Estimated Number* of New Cases for Selected Cancers by State, US, 2018
`
`Non-
`Lung Sl Melanoma Hodgkin
`Female Uterine Colon & Uterine
`Urinary
`lymphoma
`bronchus of the skin
`All sites
`breast
`cervix
`rectum
`corpus Leukemia
`; State
`bladder
`Prostate
`27,830
`3,760
`220
`2,230
`I Alabama
`1,110
`2,460
`830
`4,190
`1,380
`990
`770
`; Alaska
`160
`360
`460
`130
`140
`510
`t
`270
`120
`110
`3,550
`34,740
`Arizona
`1,810
`3,180
`1,150
`4,460
`1,880
`1,480
`2,840
`1,210
`270
`5,700
`16,130
`i Arkansas
`720
`1,260
`670
`650
`1,370
`480
`510
`2,720
`2,160
`150
`178,130
`29,360
`i California
`7,800
`15,190
`8,190
`9,830
`18,760
`1,540
`14,400
`6,610
`6,220
`25,570
`i Colorado
`1,180
`3,190
`180
`1,850
`870
`910
`2,560
`1,640
`1,100
`3,630
`21,240
`I Connecticut
`1,210
`2,220
`760
`2,700
`970
`970
`1,520
`120
`890
`3,540
`290
`640
`380
`250
`450
`180
`210
`890
`6,110
`780
`t
`Delaware
`; Dist. of Columbia
`80
`420
`240
`120
`70
`310
`120
`120
`520
`t
`3,260
`13,630
`135,170
`11,670
`19,860
`1,100
`1 Florida
`6,600
`4,770
`18,710
`7,940
`5,990
`4,450
`5,340
`56,920
`7,490
`430
`4,120
`I Georgia
`1,960
`1,590
`7,160
`3,040
`1,970
`1,600
`6,280
`i Hawaii
`260
`510
`830
`490
`270
`50
`650
`280
`200
`1,150
`8,450
`j Idaho
`490
`310
`1,060
`590
`390
`900
`290
`1,070
`630
`50
`66,330
`! Illinois
`3,190
`6,300
`2,830
`9,220
`2,980
`5,340
`2,800
`2,170
`570
`9,960
`37,250
`[ Indiana
`1,740
`3,460
`1,210
`3,190
`1,400
`5,840
`1,900
`1,600
`5,630
`290
`17,630
`( Iowa
`880
`1,580
`700
`710
`2,480
`1,050
`810
`2,560
`1,510
`110
`15,400
`\ Kansas
`660
`1,360
`2,050
`850
`640
`1,220
`530
`590
`110
`2,290
`25,990
`; Kentucky
`1,200
`2,210
`850
`5,150
`1,440
`1,060
`960
`2,370
`210
`3,720
`25,080
`I Louisiana
`1,000
`2,600
`2,310
`670
`740
`3,660
`1,040
`1,000
`210
`3,570
`j Maine
`580
`710
`380
`320
`1,450
`400
`470
`1,350
`660
`50
`8,600
`3,470
`33,810
`5,940
`2,950
`) Maryland
`1,500
`4,270
`1,690
`1,290
`220
`1,270
`910
`4,060
`2,630
`37.130
`6,490
`j Massachusetts
`2,040
`5,140
`1,650
`2,090
`1,590
`1,150
`210
`5,400
`4,510
`56,590
`8,730
`I Michigan
`3,070
`1,820
`8,780
`2,890
`2,590
`2,330
`370
`2,920
`2,270
`31,270
`I Minnesota
`1,380
`1,270
`1,420
`1,420
`3,980
`140
`1,120
`4,500
`1,370
`18.130
`1,550
`I Mississippi
`620
`560
`560
`2,690
`590
`2,240
`430
`150
`'5J60
`I Missouri
`3,000........ 1,M0
`2,890.........1,240
`1,240
`1,800
`1,480
`5750
`250
`35,520
`1,020
`I Montana
`350
`810
`230
`830
`440
`280
`220
`520
`t
`6,080
`1,560
`I Nebraska
`490
`1,310
`540
`460
`960
`380
`410
`900
`10,320
`70
`2,180
`I Nevada
`1,190
`770
`580
`2,090
`790
`130
`1,130
`410
`500
`14,060
`I New Hampshire
`520
`840
`460
`370
`360
`280
`1,230
`590
`1,360
`8,080
`t
`5,430
`8,550
`53,260
`380
`4,100
`I New Jersey
`5^870
`2,590
`1,990
`2,830
`2,370
`2,180
`9,730
`j New Mexico
`390
`1,090
`500
`410
`960
`800
`340
`360
`1,470
`80
`17,890
`110,800
`870
`9,080
`j New York
`5,440
`9,880
`4,410
`13,190
`4,920
`4,890
`4,580
`7,760
`55.130
`410
`4,440
`North Carolina
`2,530
`5,580
`2,050
`8,490
`3,310
`2,240
`1,910
`North Dakota
`200
`380
`500
`220
`170
`t
`350
`140
`150
`570
`4,110
`10,610
`68,470
`5,810
`3,350
`2,740
`2,060
`10,760
`3,400
`2,880
`480
`5,550
`Ohio
`19,030
`! Oklahoma
`890
`1,670
`860
`1,670
`710
`860
`3,210
`590
`2,870
`170
`21,520
`Oregon
`1,130
`2,040
`650
`3,140
`1,570
`1,010
`890
`1,510
`140
`3,400
`12,140
`80,960
`Pennsylvania
`7,360
`4,240
`10,470
`4,320
`3,430
`6,440
`500
`3,320
`2,930
`5,920
`Rhode Island
`360
`740
`280
`270
`460
`260
`190
`880
`1,010
`t
`3,080
`4,540
`30,450
`2,410
`220
`I South Carolina
`1,310
`4,630
`1,820
`1,150
`960
`920
`South Dakota
`260
`510
`270
`220
`170
`190
`650
`740
`5,100
`440
`t
`5,590
`36,760
`3,110
`310
`Tennessee
`2,750
`1,660
`6,030
`1,900
`1,540
`1,130
`1,370
`18,260
`121,860
`10,080
`1,360
`Texas
`4,530
`12,600
`15,460
`4,440
`5,460
`4,580
`4,000
`10,950
`Utah
`1,250
`440
`400
`480
`1,010
`520
`900
`780
`70
`1,720
`3,840
`Vermont
`250
`230
`170
`390
`270
`160
`120
`560
`600
`t
`7,510
`42,420
`Virginia
`1,900
`4,200
`5,860
`2,620
`1,760
`3,380
`1,570
`1,250
`290
`5,580
`36,170
`Washington
`1,940
`1,770
`3,730
`2,650
`1,390
`1,330
`4,810
`240
`2,710
`12,110
`i West Virginia
`620
`820
`2,060
`720
`480
`1,030
`450
`90
`390
`1,700
`3,660
`1,350
`33,340
`i Wisconsin
`1,710
`4,400
`1,740
`1,410
`2,650
`190
`1,410
`5,420
`"'2,780
`Wyoming
`330
`160
`TOO................330"
`......200..........
`.....120.........
`100
`210
`t
`450
`164,690
`140,250
`13,240
`266,120
`1,735,350
`United States
`81,190
`60,300
`234,030
`74,680
`63,230
`91,270
`‘Rounded to the nearest 10, Excludes basal and squamous cell skin cancers and in situ carcinomas except urinary bladder. tEstimate is fewer than 50 cases. These esti-
`[ mates are offered as a rough guide and should be interpreted with caution. State estimates may not sum to US total due to rounding and exclusion of state estimates
`: fewer than 50 cases.
`: Please note: Estimated cases for additional cancer sites by state can be found in Supplemental Data at cancer.org/statistics or via the Cancer Statistics Center at
`; cancerstatisticscenter.cancer.org.
`©2018, American Cancer Society, Inc., Surveillance Research
`
`Cancer Facts & Figures 2018
`
`5
`
`
`
`FILED: NEW YORK COUNTY CLERK 05/10/2019 04:01 PM
`NYSCEF DOC. NO. 141
`
`INDEX NO. 190307/2013
`
`RECEIVED NYSCEF: 05/10/2019
`
`Table 3. Estimated Number* of Deaths for Selected Cancers by State, US, 2018
`Brain/
`Non-
`Lung & Hodgkin
`Colon &
`Female
`nervous
`bronchus lymphoma Ovary Pancreas Prostate
`rectum
`breast
`Leukemia Livert
`All sites
`system
`State
`10,720
`; Alabama
`3,140
`490
`740
`240
`300
`500
`950
`400
`670
`330
`1,120
`; Alaska
`t
`t
`t
`50
`80
`60
`290
`100
`70
`t
`12,390
`I Arizona
`680
`310
`970
`2,850
`410
`680
`540
`1,040
`850
`380
`6,910
`j Arkansas
`280
`430
`2,130
`200
`150
`260
`290
`600
`410
`190
`60,650
`I California
`1,860
`3,490
`4,570
`2,140
`1,570
`11,830
`2,580
`3,900
`5,300
`4,500
`Colorado
`8,000
`510
`580
`230
`1,600
`250
`410
`340
`660
`580
`270
`6.590
`Connecticut
`320
`520
`160
`1,570
`220
`460
`290
`320
`410
`200
`2,080
`Delaware
`160
`90
`70
`50
`110
`580
`80
`140
`140
`50
`Dist. of Columbia
`t
`1,030
`90
`70
`t
`t
`80
`200
`90
`110
`t
`45,030
`Florida
`1,290
`2,260
`3,300
`1,510
`970
`2,150
`11,760
`3,640
`1,820
`2,940
`17,730
`Georgia
`870
`1,210
`530
`420
`890
`'4,650
`1,580
`620
`1,320
`500
`2,580
`Hawaii
`t
`120
`230
`100
`180
`90
`590
`230
`160
`50
`3,020
`Idaho
`200
`240
`80
`110
`120
`140
`680
`240
`210
`100
`24,670
`Illinois
`1,160
`1,680
`790
`560
`980
`1,100
`6,410
`2,080
`1,720
`620
`13,820
`i Indiana
`600
`910
`550
`3,960
`450
`290
`550
`1,110
`860
`350
`'6,570
`! Iowa
`300
`150
`460
`1,740
`250
`570
`260
`250
`370
`190
`j Kansas
`5,600
`260
`180
`120
`420
`240
`1,490
`470
`260
`350
`170
`10.590
`Kentucky
`390
`190
`660
`440
`3,530
`320
`380
`830
`580
`260
`9,370
`Louisiana
`400
`730
`290
`170
`550
`330
`2,580
`830
`610
`220
`Maine
`150
`230
`3,360
`970
`110
`60
`130
`120
`230
`180
`100
`10,780
`Maryland
`290
`530
`260
`850
`580
`2,560
`340
`420
`870
`810
`12,610
`Massachusetts
`600
`960
`380
`320
`650
`520
`3,180
`890
`750
`370
`21,380
`Michigan
`940
`1,610
`500
`5,860
`750
`1,670
`840
`880
`1,400
`570
`10,080
`Minnesota
`520
`230
`750
`410
`2,420
`380
`770
`460
`630
`300
`Mississippi
`6,750
`310
`490
`110
`170
`230
`310
`1,930
`640
`420
`220
`Missouri
`920
`550
`250
`370
`580
`3,950
`1,050
`520
`850
`13,280
`320
`Montana
`130
`150
`510
`70
`50
`80
`90
`180
`140
`2,110
`70
`[ Nebraska
`190
`70
`250
`890
`130
`130
`150
`320
`230
`3,550
`110
`I Nevada
`280
`150
`120
`380
`240
`1,380
`520
`210
`390
`5,330
`150
`i New Hampshire
`130
`70
`210
`100
`760
`80
`110
`190
`170
`2,810
`80
`I New Jersey
`750
`1,300
`510
`400
`720
`650
`3,670
`1,400
`1,250
`430
`16,040
`I New Mexico
`220
`270
`120
`110
`760
`340
`140
`240
`260
`3,750
`100
`New York
`1,680
`910
`2,760
`1,710
`1,200
`8,490
`1,460
`2,970
`2,390
`35,350
`900
`North Carolina
`940
`1,390
`610
`430
`760
`1,010
`5,770
`1,570
`1,370
`540
`20,380
`North Dakota
`t
`70
`90
`50
`t
`t
`310
`110
`60
`80
`1,290
`1,110
`1,860
`Ohio
`7,200
`550
`860
`1,040
`2,100
`1,700
`1,000
`640
`25,740
`390
`540
`Oklahoma
`270
`190
`350
`400
`2,460
`750
`530
`210
`8,470
`450
`Oregon
`620
`280
`240
`2,000
`650
`310
`480
`530
`8,310
`260
`1,880
`1,300
`Pennsylvania
`970
`670
`2,160
`1,270
`7,280
`1,180
`2,380
`28,620
`710
`Rhode Island
`100
`50
`150
`120
`610
`60
`90
`160
`130
`2,180
`50
`South Carolina
`520
`230
`730
`2,900
`300
`860
`470
`400
`710
`10,630
`270
`no
`South Dakota
`110
`80
`t
`50
`60
`440
`160
`80
`1,680
`60
`600
`960
`Tennessee
`460
`310
`4,480
`700
`1,220
`920
`540
`350
`14,900
`1,830
`Texas
`1,330
`920
`2,880
`2,700
`9,310
`3,740
`1,660
`2,880
`41,030
`1,130
`220
`Utah
`270
`110
`470
`130
`150
`170
`280
`280
`3,270
`130
`no
`60
`Vermont
`50
`t
`110
`50
`390
`50
`80
`50
`1,450
`700
`1,120
`Virginia
`490
`370
`3,780
`550
`720
`1,210
`1,090
`400
`15,260
`; Washington
`690
`950
`450
`340
`710
`3,080
`970
`520
`860
`13,030
`400
`i West Virginia
`180
`300
`150
`90
`1,470
`190
`200
`430
`280
`4,900
`110
`Wisconsin
`620
`890
`3,000
`420
`230
`450
`890
`/2U
`520
`360
`11,840
`t
`t
`70
`220
`t
`60
`t
`80
`70
`t
`980
`Wyoming
`19,910
`14,070
`44,330
`40,920
`16,830
`United States
`29,430
`30,200
`154,050
`24,370
`50,630
`609,640
`‘Rounded to the nearest 10, tEstimate is fewer than 50 deaths. tLiver includes intrahepatic bile duct. These estimates are offered as a rough guide and should be
`interpreted with caution. State estimates may not sum to US total due to rounding and exclusion of state estimates fewer than 50 deaths.
`Please note: Estimated deaths for additional cancer sites by state can be found in Supplemental Data at cancer.org/statistics or via the Cancer Statistics Center at
`cancerstatisticscenter.cancer.org.
`©2018, American Cancer Society, Inc., Surveillance Research
`
`6
`
`Cancer Facts & Figures 201 Q
`
`(J
`
`
`
`FILED: NEW YORK COUNTY CLERK 05/10/2019 04:01 PM
`NYSCEF DOC. NO. 141
`
`INDEX NO. 190307/2013
`
`RECEIVED NYSCEF: 05/10/2019
`
`Table 4. Incidence Rates* for Selected Cancers by State, US, 2010-2014
`
`Non-Hodgkin
`lymphoma Prostate Urinary bladder
`Breast Colon & rectum Lung & bronchus
`All sites
`Male Female Male Male Female
`Female Female i Male Female Male Female
`Male
`State
`129.3
`:
`Alabama
`14.0
`34.0
`7.6
`52.1
`92.5
`19.6
`119.6
`52.2
`394.9
`36.9
`533.2
`411.9
`Alaska
`9,6
`91.4
`13.5
`33.8
`67.5
`40.2
`53.3
`20.9
`125.4
`46.6
`447.7
`413.8
`Arizona
`8.0
`45.4
`13.4
`32.2
`18.4
`80.8
`56.0
`29.8
`375.0
`112.4
`39.2
`120.7
`i 112.7
`398.1
`Arkansas
`7.4
`14.8
`36,0
`20.4
`99.0
`60.7
`50.1
`37.1
`528.0
`109.3
`388.5 j 120.7
`California
`7.4
`31.4
`15.3
`39.9
`22,8
`42.5
`51.0
`32.6
`459.3
`390.2
`I 123.7
`Colorado
`32.7
`48.3
`41.6
`110,9
`21.1
`14.5
`37.9
`30.8
`445.4
`118.8
`;
`Connecticut
`458.4
`I 139.2
`34.3
`46.9
`17.2
`56,8
`25,6
`44.4
`526.7
`141.6
`'
`456.4
`I 133.1
`I Delaware
`42.2
`17,3
`25.4
`32.9
`62.9
`43.5
`570.7
`159.7
`:
`446.1 i 143.5
`[ DIst. of Columbia
`49.5
`23.3
`22.5
`13.1
`48.7
`40.3
`534.4
`103.6
`; 33.2
`Florida
`53.1
`21.0
`14.5
`32.3
`42,5
`479.4
`115.5
`396.9
`129.3
`i
`410.9
`j 123.5
`Georgia
`52.2
`14,7
`33.3
`21.9
`35.6
`534.1
`48.9
`407.4
`I 136.0
`Hawaii
`23.7
`14.6
`90,1
`38.1
`36.5
`22.1
`51.3
`444.1
`410.5
`i 120.5
`Idaho
`15.4
`119.7
`37.9
`46.8
`21.9
`32.5
`39.8
`477,5
`119.4
`130.0
`Illinois
`37.5
`23.5
`16.3
`57.8
`52.5
`38.1
`437.9
`520,1
`95.7
`425.6 j 120.1
`Indiana
`36,7
`16.1
`22.8
`38.5
`60.8
`48.8
`494.3
`112.2
`439.5 i 122.8
`Iowa
`529^’
`53.0
`38.4
`18.1
`26.9
`51.7
`39.8
`78.3
`124,1
`73.1
`24.0
`16.8
`52.8
`38,8
`47.4
`36.1
`430.0
`123.5
`Kansas!
`521.8
`i 40,2
`113.0
`472.7
`j 123.3
`590.8
`1 Kentucky
`116.3
`25.2
`16.7
`79.7
`42.4
`59.3
`:
`144.4
`420.8
`1 123.2
`Louisiana
`54.9
`33,5
`16.7
`90.8
`23.9
`56.0
`41.4
`576.5
`99.8 i
`454.0
`j 125.5
`j Maine
`47.5
`65.3
`22.8
`18.2
`42,7
`34.3
`83.9
`517.6
`131.5
`i
`42l’0
`j 131 !o
`i Maryland
`52.0
`20.7
`15.1
`37.0
`42.6
`33.3
`66.6
`502.5
`114.2
`I
`j Massachusetts
`40.5
`23.4
`16.6
`60.5
`33.7
`70.3
`136.1
`449.3
`504.1
`42.9
`126.3
`i
`426.3
`■ Michigan
`24.4
`16.9
`39.1
`77.2
`58.8
`122.2
`44.0
`34.0
`516.4
`119.4
`;
`5 Minnesota!
`38.5
`18.1
`34.7
`50.2
`61.8
`27.1
`434.6
`130.2
`43.8
`510.9
`1355
`I 30.9
`; 101.4
`407.4
`558.7
`! Mississippi
`14.3
`20.9
`41.8
`56.3
`58.2
`115.5
`101.0
`) Missouri
`427'6
`33,8
`64.3
`j
`22.6
`15.4
`49.7
`125.9
`36,6
`89.0
`502.0
`116.6
`i
`424.7
`( Montana
`36.0
`22.6
`16.3
`53.8
`44.2
`34.1
`60,9
`485.9
`123.1
`119.6
`37.1
`[ Nebraska
`16.9
`50.2
`71.8
`24,8
`38.2
`416.0
`121.1
`49.9
`507.5
`[ Nevada!!
`136.8
`39.0
`36.4
`71.9
`20.4
`14.9
`60.5
`50.7
`114.3
`403.2
`504.8
`123.5
`463.1
`140.4
`I New Hampshire
`48.1
`17.4
`40,9
`34.2
`71.2
`25.3
`63,3
`527.5
`139 A
`i 543.0
`I New Jersey
`52.5
`65.6
`41.5
`25.5
`37.8
`17.9
`132.0
`47.9
`AblS
`99.4
`:
`363.8
`I New Mexico!§
`30.5
`36.3
`49.1
`26.1
`17.6
`13.2
`112.6
`40.2
`417.1
`136.8
`I 41.0
`i 546.4
`5 New York
`54.2
`17.8
`26.3
`35.7
`69.9
`451.0
`46.9
`129.0
`125.0
`421.4
`I 527.9
`I North Carolina
`56.1
`35.5
`21,4
`14.5
`88.5
`43.7
`33.0
`129.4
`123.2
`I
`414.5
`121.4
`! 510.4
`S North Dakota
`8.7
`37.0
`18.2
`48.9
`22.8
`40.0
`70.8
`53.8
`111.8 :
`I 504.6
`j Ohio
`....122'9
`9.2
`38.6
`15.3
`59.0
`35.8
`83.7
`22.9
`47.9
`424.4
`108.3 I 33.6
`117.8
`i 502.0
`I Oklahoma
`15.0
`7.9
`22.1
`58.7
`86.6
`48.6
`36.9
`412.3
`I 467,9
`I Oregon
`101.1
`8.9
`38.0
`31.2
`53.4
`63.1
`15.8
`22.4
`419.2
`126.0
`40.8
`117.5
`:
`j
`129.8
`i 543.9
`I Pennsylvania
`11.1
`17.9
`43.9
`37.5
`56.1
`78.3
`26.0
`461.3
`49.9
`108.5
`; 518.5
`130.3
`( Rhode Island
`12.8
`45.1
`18.1
`41.2
`34.7
`77.7
`63.7
`26.5
`457.9
`121.4 i
`I 44.7
`127.2
`1 5213
`I South Carolina
`8.6
`53.7
`85.7
`34.7
`20.0
`14.0
`33.1
`411.9
`; 498.4
`■ 130.7
`j South Dakota
`8.9
`24.6
`16.1
`116.8
`35.1
`50.8
`38.8
`69.7
`51.6
`428.1
`I 529.2
`i Tennessee
`8.0
`61.0
`21.5
`14.9
`119,1
`34.5
`95.7
`36.4
`46.8
`121.1
`418.7
`i 465.1
`i Texas
`6.4
`27.4
`99.4
`32.2
`44.7
`21,5
`15.0
`68.0
`380.2
`111.5
`46.3
`130.6
`114.7
`: 457.4
`373.9
`! Utah
`6.0
`27.7
`24.1
`32.7
`15.1
`23.2
`29.8
`35.5
`98,4
`493.3
`I Vermont
`10.6
`71,8
`17.5
`59.7
`38.9
`26.5
`130.1
`33,0
`39.3
`4374
`126.9
`I
`i 460.8
`I Virginia
`8.2
`107.6
`14.1
`33.1
`73.1
`31.1
`50,8
`20.9
`41.1
`398.7
`134.9
`j
`1 Washington
`9.3
`16.7
`116,3
`37.6
`53.7
`65.5
`25,3
`32.9
`437.9
`40.9
`502.1
`^
`99,6
`i 523.7
`114.8
`1
`West Virginia
`10.5
`21.8
`16.0
`39.9
`40.9
`66.2
`98,7
`443.8
`53.1
`437.3
`: 515.8
`10.0
`54.8
`25.5
`17.3
`116.0
`39.9
`43.6
`33.6
`69.5
`127.9
`Wisconsin
`49.4 ....... 44:1............197 .......... 13.3 .....
